Cruzeiro coach Mano Menezes complained of a conspiracy against Brazilian clubs after Dede was shown a red card for a challenge that left Boca Juniors goalkeeper Esteban Andrada with a fractured jaw.
Dede was dismissed with the use of VAR after his attempt at a header saw him miss the ball and catch Andrada in the 75th minute of the Copa Libertadores quarter-final first-leg clash at La Bombonera on Wednesday.
Menezes' men were trailing to Mauro Zarate's first-half strike when the Brazil centre-back was given his marching orders, and Pablo Perez's effort eight minutes from time clinched a 2-0 win for the Superliga side.
The Cruzeiro boss was unimpressed with the decision to send off Dede and asked the Brazilian Football Confederation (CBF) to provide greater protection to their teams.
"We have VAR so we do not have great injustices in football, and we saw a great injustice. We lost a player in our best moment of the game," said Menezes, who highlighted how CONMEBOL has dealt with ineligible players in the Libertadores this season.
The governing body awarded Independiente a 3-0 win over Santos after the Brazilian side fielded Carlos Sanchez in their last-16 first leg despite a suspension, while Boca and River Plate avoided punishment for selecting Ramon Abila and Bruno Zuculini respectively despite bans.
"Someone who wasn't on the field thought something was different. No Boca player did – so much so that they thought it was something against them," added Menezes.
"The referee made the decision and he is to blame for everything that happened.
"The referee wanted to dismiss Dede, and the problem is there are a lot of things against Brazilian teams. There was the case of Santos, the lack of punishment applied to River and Boca. Things are very different.
"It's something that doesn't smell good. I think the CBF and other federations have to take a stand. This is something serious. It has to be treated by Brazilian clubs seriously."
Andrada is expected to miss the Superclasico between Boca and River at La Bombonera on Sunday and Guillermo Barros Schelotto backed the process behind Dede's dismissal.
"They must have had some reason for the red card," said the Boca head coach.
"There is the referee on the pitch and another three watching the VAR, and I think the situation is very clear, they will have had a reason to throw Dede out.
"When we play with VAR we have to respect the law more than ever because not only is there the referee on the pitch, but there are also three others out watching everything that happens."
18 de marzo 2019
|Napoli goalkeeper Ospina given all clear after head injury|
|Captain Morgan signs Leicester extension|
|Tennis Canada coach Labelle says ´sky is the limit´ for Andreescu|
|Pochettino happy at Tottenham but hints at Real Madrid interest|
|´Shocked´ Hudson-Odoi called into England squad|
|Barca talk will not affect underrated Griezmann - Deschamps|
|Overmars extends Ajax contract amid Arsenal links|
|Tiger commits to WGC-Dell Match Play ahead of Masters|
|Rashford: Aguero is Premier League´s most complete striker|
|Ineos reports ´ideal´ for Team Sky, says Wiggins|
|An offer we couldn´t refuse - Giants GM Gettleman breaks silence over Beckham trade|
|Godfather II was better - Monchi defends Sevilla sequel|
|Hall: CSA must avoid exodus of Kolpak youngsters|
|RFL to consider New York rugby league club|
|Bierhoff: Germany not in doomsday scenario|
|Jorginho is playing well - Mancini defends much-maligned Chelsea midfielder|
|I´m retiring from the NFL on top! - Ngata bows out on Kilimanjaro|
|Mancini challenges Balotelli to earn Italy recall|
|Arthur given time to earn new Eels deal|
|Chelsea say player was racially abused during Dynamo Kiev game|
|Quins land Argentina playmaker Landajo|
|F1 2019: What we learned from Australian Grand Prix|
|Tour de France 2020 opening stages provide stiff challenge|
|Mata: Defeats will test Man Utd spirit|
|Wigan ´seeking clarification´ over Edwards´ intentions|
|Barca confirm two-week absence for Suarez|
|Walton defends LeBron after Knicks defeat|
|Ronaldo charged by UEFA after Atletico celebration|
|Ward-Prowse called up by England as Delph, Stones and Loftus-Cheek withdraw|
|Del Potro follows Nadal in missing Miami Open|
|Leeds centre-back Jansson out for three weeks|
|Thiem: Indian Wells triumph feels like grand slam glory|
|River Plate star Quintero suffers ruptured ACL|
|Rahmat and Ihsanullah seal historic Test win for Afghanistan|
|Brewers spoof Mean Girls during spring training|
|Truly a Cinderella story - Andreescu visualised unlikely Indian Wells win|
|Busquets takes pride in majestic Messi|
|Dani Alves, Kanoute and Monchi´s best Sevilla signings|
|Matic backing Solskjaer stay despite United wobble|
|Federer: Thiem has the ´secret´ to achieve greatness on clay|
|76ers top Bucks despite Antetokounmpo´s 52 points|
|MLS Review: Waston creates history on day to remember for FC Cincinnati|
|Tuchel applauds PSG´s mental strength as fans protest during Le Classique|
|Busch secures 200th NASCAR victory after overcoming penalty in California|
|Thiem shocks Federer to clinch first Masters 1000 title in Indian Wells|
|Spalletti: Inter have ´found a striker´ in Lautaro|
|Luckily I didn´t see it or I would´ve thrown myself in too – Gattuso fumes at Kessie-Biglia row|
|Pique not planning another Griezmann documentary amid Barcelona speculation|
|Kessie, Biglia apologise for derby bench row|
|Napoli keeper Ospina kept in hospital after head injury against Udinese|
|Valverde: Betis win an important step for Barcelona|
|Crowd disturbances force abandonment of Panathinaikos-Olympiakos|
|McIlroy eyes Augusta after Players Championship success|
|Suarez sprains ankle as Barcelona beat Betis|
17 de marzo 2019
|Silva lauds Pickford after Chelsea shut out|
|Messi grateful for Betis ovation after breaking Barcelona record|
|Brilliant Andreescu stuns Kerber to win Indian Wells title|
|I need every Manchester City player for run-in - Guardiola|
|Barcelona beat Betis despite surprising possession statistic|
|Paris Saint-Germain 3 Marseille 1: Di Maria produces a Classique performance|
|McIlroy seals Players Championship victory|
|I am happy here – James expects Bayern Munich and Real Madrid to open transfer talks|
|Messi surpasses Xavi to record most Barcelona wins|
|Real Betis 1 Barcelona 4: Record-breaker Messi sends leaders 10 points clear|
|AC Milan 2 Inter 3: Martinez penalty proves decisive in derby thriller|
|Mainz 06: Bundesliga club troll themselves after Bayern Munich thrashing|
|Goal-shy Higuain must improve - Sarri|
|Wales dominate Six Nations Player of the Championship shortlist|
|Sarri confounded by Chelsea´s second-half surrender|
|Tiger ´right on track´ despite disappointing week as Furyk catches leaders|