Frank de Boer's Atlanta United suffered another defeat as their stuttering MLS title defence continued, while Nani's late winner saw Orlando City past Vancouver Whitecaps.
Lowly Atlanta were upstaged by FC Dallas 2-1 on Saturday – leaving De Boer's side without a victory at home in the league this season.
Atlanta attempted 22 shots at Mercedes-Benz Stadium, where Jesus Ferreira and Bryan Acosta silenced the hosts.
Josef Martinez converted a penalty deep into stoppage-time but it was merely a consolation for Atlanta, who have only won three games in all competitions since former Inter and Crystal Palace boss De Boer replaced Gerardo Martino.
Plenty of chances to build on.— Atlanta United FC (@ATLUTD) April 21, 2019
Highlights from today's match pic.twitter.com/yWSk2Rsea5
Atlanta are second from bottom in the Eastern Conference with five points from six matches, while Dallas are fourth in the west.
Ex-Manchester United winger and Portuguese star Nani led Orlando to a 1-0 win against the visiting Whitecaps.
Nani deflected Sacha Kljestan's 88th-minute shot beyond Vancouver goalkeeper Zac MacMath for his fourth MLS goal since arriving from Sporting CP.
Former Atletico Madrid midfielder Nicolas Gaitan set up two goals in Chicago Fire's 4-1 rout of winless Colorado Rapids, who ended the match with 10 men.
After Colorado's Kei Kamara cancelled out Nemanja Nikolic's opener prior to half-time, the Fire scored three unanswered goals following the break via Charles Sapong, Djordje Mihailovic and Aleksandar Katai.
Rapids midfielder Jack Price was sent off with four minutes remaining in Chicago to compound Colorado's misery.
Elsewhere, New England edged New York Red Bulls 1-0, Portland Timbers ended their winless start to the season by defeating Columbus Crew 3-1, Philadelphia Union accounted for Montreal Impact 3-0 and San Jose Earthquakes crushed Sporting Kansas City 4-1.
22 de mayo 2019
|Leclerc keen to end drought at ´special´ Monaco GP|
|Wawrinka and Fucsovics upset in Geneva|
|Viviani concludes disappointing 2019 Giro bid|
|FIFA abandons plans for 48-team World Cup in Qatar|
|AFC Champions League Review: Guangzhou Evergrande squeeze through, Kashima Antlers´ title defence co|
|Sabalenka through on busy day in Strasbourg|
|Hamilton excused from media duties after Lauda´s death|
|Arsenal did not offer Ramsey new deal due to ´salary balance´ concerns|
|Hales hopes England door not closed, targets T20 World Cup|
|Ter Stegen out of Copa del Rey final|
|Ewan victory sees Demare nudge into Giro points lead|
|Khawaja sent for scans after blow to head|
|Diego Costa a doubt for start of Atletico´s pre-season with ligament sprain|
|Caballero commits to Chelsea for 2019-20|
|F1 Raceweek: Ricciardo or Red Bull to halt Mercedes? - Monaco GP in numbers|
|Deco: Valverde will be feeling heat at Barcelona after Liverpool loss|
|Caparros to be replaced as Sevilla coach but remain at the club|
|England have no margin for error at World Cup, warns Stokes|
|An iconic character - Villeneuve & Prince Albert remember Niki Lauda|
|Borussia Dortmund sign Leverkusen star Brandt|
|Rudi Garcia to leave Marseille|
|If my job depends on one game, I want to leave Chelsea immediately – Sarri|
|Sarri hopes Hazard stays at Chelsea but will respect any decision|
|NRL Opta facts: Retiring Cronk seeks 100th try|
|Trail Blazers give coach Terry Stotts multi-year extension|
|Guingamp and coach Gourvennec part ways following relegation|
|Coutinho returns to Barcelona training ahead of Copa del Rey final|
|Lam signs new long-term contract with Bristol|
|Aduriz agrees one-year Athletic extension|
|Those Star Wars writers might have been busy! Rodgers unhappy with Game of Thrones finale|
|He should have a statue in Perez´s garden – Real Madrid great lauds Zidane´s return|
|Gyan makes Ghana retirement U-turn after presidential request|
|49ers pass rusher Bosa tweaks hamstring|
|Kroos, Ter Stegen to miss Germany qualifiers|
|Archer brings X-factor to England attack – Root|
|Thorgan Hazard completes Borussia Dortmund move|
|Giannis not feeling pressure despite Raptors revival|
|Gundogan confident Man City will keep Sane despite Bayern links|
|Sterling wants to discuss tackling racism with FA and Premier League|
|Raptors´ VanVleet ends shooting slump after birth of second child|
|Pogba and Hazard to Real Madrid? It´s possible, says Varane|
|Plunkett hails ´special talent´ Archer|
|Solskjaer deserves patience at Manchester United - Van Persie|
|Yankees stay hot, pull away for win over Orioles|
|Three takeaways from Raptors´ Game 4 win over Bucks|
|Well-rounded Raptors level series against Bucks|
|Blues snap 49-year Stanley Cup Finals drought|
|Koscielny slams UEFA after Mkhitaryan withdrawal|
|Del Bosque defends Spanish clubs despite European failure|
|Pulisic keen to match Hazard impact at Chelsea|
|Durant ´100 per cent undecided´ about future, says manager|
|Rodgers says Packers´ new offense is ´going to look different´|
|Beilein explains decision to leave Michigan for Cavaliers|
|Warriors became ´unbeatable´ with Durant, says Green|
|Simeone reaffirms Atletico commitment ahead of rebuild|
|Wallabies star Sio re-signs until 2022|
|Lacazette adamant he´s in the form of his life|
|Cech denies he already agreed to Chelsea sporting director role|
|Fury expects Wilder rematch in March or April 2020|
|Costa avoids bone damage after suffering ankle injury|
21 de mayo 2019
|Canada beat USA, who must now face rampant Russia|
|Barty withdraws before rain scuppers play in Strasbourg|
|AFC Champions League Review: Oscar hat-trick helps Shanghai SIPG progress|
|Zverev cruises through in Geneva as Dimitrov crashes out|
|Luka Doncic & Trae Young top 2018-19 NBA All-Rookie first team|
|F1 Raceweek: Can Verstappen stop Hamilton & Bottas in Monaco?|
|Sri Lanka end ODI winless streak in Edinburgh|
|Ratchford set for long injury absence|
|It´s staying up! - Bernardo Silva shows off good-luck Christmas tree|
|Varane vows to stay at Real Madrid for next season|